HCG norms by week. HCG level during pregnancy by days from conception What is hCG at 5 weeks
HCG calculator will help decipher the results of a blood test for hCG over time from the date of conception, embryo transfer (after IVF) or delay, determine the duration of pregnancy and assess the dynamics of growth in hormone levels.
HCG doubling period in singleton pregnancy
HCG begins to be produced already 6-10 days after fertilization of the egg. In the first weeks, your hCG levels should double approximately every 2 days. As the gestational age increases, the rate of its growth slows down - when the level reaches 1200 mU/ml, hCG doubles every 3-4 days (from 72 to 96 hours), and after 6000 mU/ml the doubling occurs on average every 4 days (96 hours).
PM - according to the date of the last menstruation.
DPO - days after ovulation.
The concentration of hCG reaches its maximum at 9-11 weeks of pregnancy, then the level of hCG begins to slowly decrease.
During multiple pregnancies, the hCG content increases in proportion to the number of fetuses, and on average, hCG levels in pregnant women with twins (triplets) are usually higher than in other pregnant women at the same stage.
Laboratory standards and user results
HCG norms May vary from laboratory to laboratory. This is due to the use of various research techniques, reagents and other factors. Therefore, to correctly assess the dynamics of hormone growth, it is necessary to conduct research in one laboratory and evaluate the results relative to the standards of this laboratory. The hCG calculator allows you to evaluate your results relative to the standards of different laboratories:
The results of other users on the graph may also differ (depending on laboratory standards) and contain errors (for example, data was entered incorrectly).
The level of hCG changes differently over the weeks of pregnancy: this hormone begins to be synthesized already in the first hours after conception, and by the end of the 3rd obstetric month of pregnancy its concentration increases several times. Let's try to figure out what hCG affects during pregnancy and how its level is related to the period.
What is hCG?
HCG - human chorionic gonadotropin. This hormone belongs to the category of gonadotropic, i.e. it directly regulates the functioning of the reproductive system. It is synthesized by the fertilized egg, or more precisely, by its part, the trophoblast, from which the placenta will later form. Increased production of hCG begins at the moment when the chorionic villi of the embryo begin to grow into the endometrium of the uterus during the process of implantation. Normally, hCG above 5 mIU/ml can only be observed in female body and only if conception occurs. That is why it is also called the pregnancy hormone. In the absence of conception, an increase in the level of this hormone may indicate the development of pathological processes, in particular the formation of tumors in men and women.
What does hCG affect?
hCG on early stages pregnancy regulates many changes in the functioning of the reproductive system.
Synthesis of other hormones
Due to the increase in hCG levels during pregnancy, the production of other important hormones is activated. The first is estrogen, it promotes the proper development of the baby, supports a number of physiological changes in a woman’s body during the process of bearing a child, prepares her body for lactation. The second hormone is progesterone. It “works” primarily to create optimal conditions for the preservation and development of the fetus: prepares the uterus for proper implantation, balances the effect of estrogen, relaxes ligaments and muscles, accumulates subcutaneous fat for a pregnant woman to “reserve” the necessary nutrients for the fetus.
What does the “pregnancy hormone” affect?
Preservation of the corpus luteum
The corpus luteum, or luteal body, is a temporary endocrine gland. It is formed after ovulation, when a mature egg leaves the follicle. If conception occurs in the current cycle, then until approximately 4 months of pregnancy the corpus luteum will participate in the development of the embryo and its nutrition. Afterwards, all its functions will be taken over by the placenta.
Blocking immune aggression
A woman’s body perceives an implanted embryo as a threat. He tries to “defend himself” and attacks him. To maintain pregnancy, it is necessary to suppress the immune aggression of the mother’s body towards the fetal cells. This process is largely influenced by human chorionic gonadotropin.
“Triggering” anatomical and physiological changes in the body of the expectant mother
In simple terms, human chorionic gonadotropin puts a woman’s body into “pregnant” mode. Indirectly or directly, it influences almost all processes, in particular, it ensures the correct formation and normal functioning of the placenta.
Effect on sexual differentiation in boys
Thanks to hCG, the genital organs of boys develop according to the male type. In addition, this hormone will stimulate the baby's gonads and adrenal glands.
HCG regulates the development of pregnancy in the early stages
Why is an hCG test prescribed during pregnancy?
Blood for hCG during pregnancy is donated primarily in order to accurately establish the fact of its occurrence. Unlike pharmacy tests, such an analysis excludes any errors due to non-compliance with instructions and incorrect interpretation of the result. Sometimes a woman is recommended to be tested several times: assessing the growth of hCG levels over time allows you to make sure that pregnancy is developing normally in the early stages. This parameter is especially important in cases where the couple was planning a child or went to a specialized clinic for assisted reproductive technologies.
Using hCG, you can approximately determine the duration of pregnancy, as well as such a feature as the number of fetuses. If a woman is expecting twins or triplets, the concentration of human chorionic gonadotropin will be several times higher than usual.
Moreover, the hCG indicator during early pregnancy is also taken into account when conducting the so-called double test as part of the first prenatal screening. The purpose of this study, which is always carried out “in conjunction” with a detailed ultrasound, is to exclude severe abnormalities in the development of the fetus. An increase in β-type chorionic gonadotropin during a singleton pregnancy may be a symptom of Down syndrome, the presence of diabetes mellitus in the expectant mother, or the development of severe toxicosis requiring medical supervision. If the indicators, on the contrary, are reduced, it is necessary to exclude Edwards syndrome, placental insufficiency and other factors that increase the risk of miscarriage.
Why do you need an hCG test during pregnancy?
Beta-hCG: normal during pregnancy
The structure of human chorionic gonadotropin contains two subunits - alpha and beta. Alpha corresponds to similar subunits of pituitary hormones and is not considered in studies for expectant mothers. When hCG levels are determined during pregnancy, the beta subunit is usually considered. This is what is recognized by the reagents used in all types of pharmacy tests, as well as by the markers used in laboratory tests.
HCG levels normally begin to double during pregnancy immediately after implantation, approximately every two days. Its growth depending on individual characteristics in the expectant mother’s body continues for 8-10 obstetric weeks (that is, from the day of the last menstruation) and reaches “record” levels at the end of the first trimester. After this, with normal fetal development and the correct course of physiological processes, the concentration of human chorionic gonadotropin decreases. By 18-20 weeks obstetric pregnancy The hCG level stabilizes and remains at the same level almost until birth.
How do hCG levels change?
In blood plasma increased level HCG during pregnancy is monitored already on the 9-10th day after ovulation. If, for example, a couple was planning a child and monitoring the phases of the cycle, already 5-6 days before the expected date of the start of menstruation, the woman can take the first test. Human chorionic gonadotropin is processed in the kidneys and excreted from the body along with urine. The principle of operation of pharmacy pregnancy tests is based on this fact. Their simplest and most inexpensive models give accurate results within 28-30 days after the start of the last menstruation. More sensitive electronic tests can be used before the delay.
The normal dynamics of the increase and decrease in hCG levels during pregnancy makes it possible to control its course at different stages.
HCG in the 2nd week of pregnancy
The second actual week of pregnancy usually occurs at the very end of the current menstrual cycle. With a duration of 28-30 days, ovulation should have occurred on days 12-15. If at this time the egg meets the sperm, we can talk about conception. Over the course of several days, usually no more than 3-5, the embryo formed by the fusion of germ cells continues to move from the fallopian tubes into the uterine cavity. There it begins to implant: the chorion villi of its shell grow into the endometrium, softened under the influence of hormones, due to which metabolic processes are launched between the organisms of the mother and the fetus. It is at this time that the synthesis of human chorionic gonadotropin is activated. Without pregnancy, the hCG level does not exceed 1.5-5 mIU/ml. On the 9-10th day after ovulation, its maximum concentration can be 5.3-13.1 mIU/ml, on the 12th day - from 20 to 59 mIU/ml.
Pregnancy tests react to a specific level of hCG
What is hCG in the 2nd week of pregnancy? Normally 14 days after ovulation, i.e. approximately at the end of the current menstrual cycle or on the first day of delay, the level of human chorionic gonadotropin can vary from 50 to 300 mIU/ml. Thanks to this, it is “recognized” with maximum accuracy by any pharmacy test with a sensitivity of more than 25 mIU/ml. Three-digit numbers in a blood test for hCG also confirm pregnancy.
HCG at 4-5 weeks of pregnancy
The 4th-5th obstetric week of pregnancy coincides with the age of the embryo at 2-3 weeks. At this time, the blastocyst, inside which the embryo develops, has already implanted in the uterine cavity and is rapidly developing. At the same time, the process of formation of the placenta begins, the uterus becomes round - this can be noticed by the doctor during palpation and by the ultrasound diagnostician during examination. The delay at this period exceeds 5-7 days, so any woman who has an idea about the duration of her menstrual cycle will probably think about pregnancy.
Absolutely precise timing real pregnancy It is almost impossible to determine, because it is impossible to know the specific day when the egg united with the sperm and the embryo implanted in the uterus. That is why most tables with hCG norms by week of pregnancy indicate a fairly large range of possible indicators.
In the first weeks, hCG levels double every two days
Thus, the hCG norm at the 3-4th week of pregnancy is on average 2000 mIU/ml, and the tolerance limits vary from 1500 to 5000 mIU/ml.
The average hCG level at the 4-5th week of pregnancy is 20,000 mIU/ml, with acceptable limits of 10,000-30,000 mIU/ml. At 5-6 weeks, the corresponding norms lie in the range of 20,000-100,000 mIU/ml.
HCG level at 6-7 weeks of pregnancy
At the 6th obstetric week of pregnancy, the uteroplacental blood flow is actively formed, by the end of this period the baby’s heart is already beating. At the 7th week, due to hormonal and physiological changes, they make themselves known. early signs pregnancy - toxicosis, weakness, high fatigue, decreased performance and others subjective feelings. Many of them are associated, among other things, with increased levels of human chorionic gonadotropin, which helps the development of the placenta.
At the 6-7th week of pregnancy, the hCG norm is in the range of 50,000-200,000 mIU/ml. An analysis for this hormone can be prescribed if you need to make sure that the pregnancy is progressing correctly, because it is in the next 4 weeks that cases of fetal development most often occur.
HCG helps the placenta develop
HCG at 8 weeks of pregnancy
By the end of the second obstetric month, the baby grows from one cell into an embryo with a complex structure of the body - it already has a brain and spinal cord, as well as a cerebellum, eyes and ears are visible, the rudiments of limbs with joints are formed. Various changes are also constantly taking place in a woman’s body: the uterus increases to 8 cm, the mammary glands become more sensitive, hormones continue to affect well-being and toxicosis. The development of the placenta during this period accelerates, and at the same time the concentration of human chorionic gonadotropin in the blood plasma and urine continues to increase.
So, at the 8th week of pregnancy, the hCG level can vary from 40,000 to 200,000 mIU/ml. Such record levels can persist for 1-2 weeks, after which the hormone level will begin to gradually decrease.
HCG norm at 12 weeks of pregnancy
At the end of the 3rd obstetric month of pregnancy, the placenta gradually begins to work; it takes on more and more functions related to nutrition and protection of the baby, so the level of human chorionic gonadotropin becomes less and less every day. The average for the 12th week of pregnancy is considered to be 55,000 mIU/ml, and the tolerance limits are 27,500-110,000 mIU/ml.
HCG level by week of pregnancy: reference table
The hCG norm by week in the first half of pregnancy is as follows:
You need to understand that only a specialist can interpret the analysis result. The given figures cannot be called reference, and when deciphering it is necessary to start from the health characteristics of a particular woman. The gestational age according to the hCG table can only be determined conditionally, and it will be more correct to calculate the PDR using the results of the analysis and the human chorionic gonadotropin calculator, according to last day menses.
More accurate results pregnancy period based on hCG levels can be obtained by women who have used IVF. In this case, the count is carried out from the day of transfer of cultured embryos of different ages or from the day of puncture.
HCG table by day during pregnancy with IVF
Elevated beta-hCG levels during pregnancy
By assessing the hCG level over time, the doctor can monitor the course of pregnancy. Sometimes it happens that this indicator turns out to be significantly greater than the upper reference value for the period. In this case, you need to check:
- multiple pregnancy with two or more embryos;
- absence of chromosomal pathologies and other developmental anomalies in the fetus;
- trophoblastic tumors;
- diabetes mellitus in a pregnant woman.
In the double test of the first prenatal screening, when hCG increases during pregnancy, additional examination is carried out. It allows you to exclude trisomy 21 and the associated Down syndrome. If such a pathology is suspected, hCG turns out to be almost 2 times too high, and the bone of the bridge of the nose is not visualized on ultrasound.
HCG, several times higher than the level of 500,000 mIU/ml, may be a signal of danger for pregnancy - if there is severe detachment of the ovum and there is a risk of fetal development faltering. Another pathology in which the concentration of human chorionic gonadotropin is below normal is the so-called hydatidiform mole, in which part of the chromosomes are “expelled” from the fertilized egg. This severe condition can cause a variety of delayed problems, including metastases and chorionic carcinoma. If extremely high levels of hCG are detected at the beginning of pregnancy and with a number of accompanying symptoms (uncontrolled vomiting, uterine bleeding, preeclamptic signs, etc.), you should seek emergency medical help as quickly as possible.
Why might it be high level HCG?
Why do hCG levels decrease?
Low hCG levels in the early stages can be a symptom of a number of problems during its course. Insufficient concentration of this hormone often accompanies the development of Patau and Edwards syndromes in the fetus. Also, a weak increase in indicators may be associated with implantation of the embryo not in the uterine cavity, but in the fallopian tube. An ectopic pregnancy is a dangerous condition that can not only harm a woman’s reproductive health, but also pose a threat to her life. This condition is diagnosed by transvaginal ultrasound, when the fertilized egg in the uterus is not visualized.
HCG in early pregnancy can drop sharply with anembryonia and antenatal fetal death. Frozen pregnancy is caused by various factors. If we're talking about about chromosomal pathologies, then a non-viable embryo stops developing, as a rule, before the 10th week. Also, such phenomena can be a consequence infectious diseases and advanced endometritis. Abnormalities in the structure of the uterus and thrombophilia, when blood clotting processes are disrupted, also lead to malnutrition and subsequent death of the embryo.
For a woman, motherhood is not only nine months of anxious anticipation and the joy of a long-awaited meeting with the baby. For an expectant mother, the entire period of pregnancy is a lot of stress for the body. Many functions and some organs undergo changes. The psycho-emotional background of the expectant mother is also not stable.
As a rule, a gynecologist who monitors the course of a woman’s pregnancy periodically prescribes tests for her. This is done in order to adequately assess whether everything is normal. Among the numerous laboratory tests, there is one test called hCG. It is very informative. For the expectant mother and for the gynecologist at the beginning of pregnancy, the hCG level is a key indicator of the presence of fertilization, and it can also be used to quite accurately determine the date of the expected birth.
What is hCG?
First, you need to say how this mysterious abbreviation stands for. HCG is human choriotic gonadotropin.
This is a hormone that is produced by the cells of the embryonic germinal membrane after the fertilized egg attaches to the lining of the uterus.
There are two substances of this hormone: alpha-hCG and beta-hCG. The first of the substances is very similar to other human hormones. Beta-hCG is unique in nature and is released only during pregnancy. This hormone allows a woman to preserve the fetus in the earliest stages. During this period, the immune system does everything possible to eliminate foreign body. This is how a woman’s body’s defenses perceive the unborn baby. It is human chorionic gonadotropin that suppresses the immune response and maintains pregnancy. When determining the content of beta-hCG, a blood test will be more informative, since all pharmacy rapid tests react to both fractions of the hormone.
There are certain statistics about the onset of production of this hormone. In the vast majority of cases, the formation of hCG in the body of a pregnant woman begins 7-10 days after fertilization. The concentration of this hormone reaches its peak levels at 11-12 weeks. After this period, the hCG level begins to gradually decrease and stabilizes by mid-pregnancy. Further, its concentration remains stable and decreases slightly immediately at the time of birth.
How is hCG content determined?
Determination of the presence of hCG and its concentration can be carried out in the blood or urine of a pregnant woman. It is these biological fluids that are subject to laboratory testing.
There is some evidence that the release of this hormone into the blood occurs faster by several weeks. By taking this test, you will be able to find out about the fact and duration of pregnancy earlier.
In order to determine the level of hCG in urine, it is not at all necessary to contact a laboratory. The pharmacy sells a variety of pregnancy tests. These modern miniature devices can not only confirm the fact of fertilization, but also provide information about the concentration of hCG in a woman’s urine. Every representative of the fair sex knows perfectly well what two stripes on such a test indicate. The objectivity of this verification method, according to its manufacturer, is 98-99%. However, in order to accurately verify the level of hCG, a woman should entrust a laboratory analysis.
When is the best time to donate blood for hCG?
It is known that the concentration of human choriotic gonadotropin begins to increase already in the first days after fertilization of the egg. According to statistics, in 5% of women the level of hCG increases already on the 8th day after conception.
In the vast majority of pregnant women, the concentration of this hormone begins to increase by the 11th day from the moment of fertilization of the egg. If a woman does not know the exact date of conception, then she should donate blood for an hCG test 3-4 weeks after the start of her last menstruation. In this case, the expectant mother usually detects a delay of several days.
Quite often, gynecologists recommend that a woman be tested for choriotic gonadotropin twice with a time interval of a couple of days. If a repeat analysis shows an increased level of hCG relative to the first result, the doctor will note the dynamics of growth and confirm the presence of pregnancy.
Usually within a few days the concentration of gonadotropin increases by 1.5-2 times. If the opposite picture is observed, that is, the level of the hormone is stably low or has decreased, then fertilization of the egg has not occurred.
When taking an analysis, it is very important to find out the standards adopted in this particular laboratory. The fact is that these indicators may differ in different institutions.
How to prepare for the hCG test?
There is no need for any special preparation. If a woman is taking a drug containing hormones, she must inform the doctor and laboratory assistant about this. Some medications, especially with progesterones, can affect the results of the study. It is best to take a blood test in the morning on an empty stomach.
What is the normal hCG level for a non-pregnant woman?
Often women undergo this test, regardless of whether they are pregnant or not. Sometimes a gynecologist recommends checking your hCG level if you suspect certain diseases, such as fibroids or ovarian cancer. The concentration of this hormone, along with other examination methods, can directly indicate the presence of the disease.
Normally, the hCG level in a non-pregnant woman should be 0-5 mU/ml. In women during menopause, due to changes in the body, the content of this hormone reaches 9.5 mIU/ml. If the analysis reveals a high level of hCG, this may be caused by the following reasons:
- A reaction to substances in a woman’s blood similar to hCG.
- This hormone is produced by the patient's pituitary gland.
- A woman is taking medications containing hCG.
- The hormone is produced by a tumor of an organ.
In cases where hCG is elevated and pregnancy is not detected, the patient undergoes a full diagnosis and receives appropriate treatment.
HCG levels during pregnancy
As mentioned earlier, after implantation of the fertilized egg has occurred, the chorion begins to produce hCG. This is how the embryo tries to survive in this still hostile world.
A woman's hormonal background begins to change. The hCG level begins to rise quite quickly in the days following conception. But immediately after conception it is not advisable to rush to get tested in a laboratory. During this period, as a rule, the result will not show an increase in hCG concentration. In order for laboratory diagnostics to detect pregnancy, at least 7-8 days must pass from the moment of fertilization. But gynecologists do not recommend forcing things and performing an analysis after a delay in menstruation.
- A result of up to 5 mU/ml is accepted in international medical practice as negative.
- An indicator of 5-25 mU/ml is considered doubtful; after a few days it is necessary to take a second test to monitor the dynamics.
- A deviation from the norm is considered to be a difference of more than 20%. If the result differs from the standard indicators for this period by 50% or more, then we are talking about a pathological phenomenon. If the deviation from the norm is 20%, then the patient is sent for a repeat test. If it showed an increase in the indicator of difference from the standards, then they talk about the development of pathology. If a deviation of 20% was confirmed, or a lower result was obtained, then this is considered a variant of the norm.
A single laboratory test of the level of choriotic gonadotropin is practiced very rarely. This may only be relevant at the beginning of pregnancy. Basically, a series of periodic tests are prescribed at a certain time interval. In this way, the dynamics of changes in the level of hCG are observed and pathological conditions are identified, such as the threat of interruption, fetoplacental insufficiency and others.
How does hCG change by day of pregnancy?
In order to assess how the hCG level changes by day of pregnancy, you need to carefully consider the table provided below.
Age of the embryo by days after conception | HCG level, honey/ml | ||
Average | Minimum | Maximum | |
7 | 4 | 2 | 10 |
8 | 7 | 3 | 18 |
9 | 11 | 5 | 21 |
10 | 18 | 8 | 26 |
11 | 28 | 11 | 45 |
12 | 45 | 17 | 65 |
13 | 73 | 22 | 105 |
14 | 105 | 29 | 170 |
15 | 160 | 39 | 240 |
16 | 260 | 68 | 400 |
17 | 410 | 120 | 580 |
18 | 650 | 220 | 840 |
19 | 980 | 370 | 1300 |
20 | 1380 | 520 | 2000 |
21 | 1960 | 750 | 3100 |
22 | 2680 | 1050 | 4900 |
23 | 3550 | 1400 | 6200 |
24 | 4650 | 1830 | 7800 |
25 | 6150 | 2400 | 9800 |
26 | 8160 | 4200 | 15 600 |
27 | 10 200 | 5400 | 19 500 |
28 | 11 300 | 7100 | 27 300 |
29 | 13 600 | 8800 | 33 000 |
30 | 16 500 | 10 500 | 40 000 |
31 | 19 500 | 11 500 | 60 000 |
32 | 22 600 | 12 800 | 63 000 |
33 | 24 000 | 14 000 | 38 000 |
34 | 27 200 | 15 500 | 70 000 |
35 | 31 000 | 17 000 | 74 000 |
36 | 36 000 | 19 000 | 78 000 |
37 | 39 500 | 20 500 | 83 000 |
38 | 45 000 | 22 000 | 87 000 |
39 | 51 000 | 23 000 | 93 000 |
40 | 58 000 | 58 000 | 108 000 |
41 | 62 000 | 62 000 | 117 000 |
From this table we can conclude that the hCG level by day of pregnancy changes quite dynamically in the first weeks after ovulation, then the rate decreases slightly and the level reaches stable levels.
At first, it takes 2 days for gonadotropin levels to double. Further, from period 5-6, it takes 3 days for the hCG concentration to double. At 7-8 weeks this figure is 4 days.
When pregnancy reaches a period of 9-10 seven-day periods, the hCG level reaches its peak values. By the 16th week, this factor is close to the concentration of the hormone in the 6-7 period. Thus, the level of hCG in the early stages changes quite dynamically.
After the 20th week of pregnancy, the concentration of hCG does not change so dramatically. Once every 10 seven-day calendar periods, the hormone level increases by approximately 10%. Only on the eve of birth does the hCG level increase slightly.
Experts explain this uneven growth of human chorionic gonadotropin to the physiological characteristics of a pregnant woman. The initial increase in hCG levels is due to the intensive development of the size of the fetus, placenta and hormonal changes in the body of the expectant mother. During this period, the chorion produces a large amount of gonadotropin to prepare a place for the baby and provide optimal conditions for its development. After the 10th week, the placenta changes significantly. From this moment on, her hormonal function fades away. The placenta is transformed into the main organ of nutrition and respiration in the mother-fetus system. It is thanks to this important element that the baby receives all the substances necessary for growth and development, as well as vital oxygen. Therefore, during this period there is a decline in the dynamics of hCG concentration.
What are the hCG levels by week?
It is very convenient to see how hCG levels change during pregnancy week by week. In the 3-4 seven-day period it is 25-156 mU/ml. Already at 4-5 weeks, the concentration of the hormone increases: 101-4870 mU/ml. By the 5th-6th period, the hCG content becomes equal to 1110-31,500 mU/ml. At 6-7 weeks, the hormone concentration changes to 2560-82,300 mU/ml. The hCG level after the 7th seven-day period rises to 23,100-151,000 mU/ml. In the 8th-9th period, the hormone content falls within the range of 27,300 - 233,000 mU/ml. For a period of 9-13 weeks, indicators of 20,900-291,000 mU/ml are considered normal. By the 13th -18th period, the hCG level decreases to 6140-103,000 mU/ml. From the 18th to the 23rd week, the hormone concentration remains at the level of 4720-80 100 mU/ml. Further, the hCG content decreases slightly. From the 23rd to the 41st week it remains at the level of 2700-78,100 mU/ml.
How to compare laboratory data with standards?
Having received laboratory test data, expectant mothers rush to find out whether they correspond to the norm. When comparing your results with the above indicators, you should take into account one very important circumstance. The text indicates obstetric weeks, which doctors count from the date of the last menstruation.
The level of hCG during pregnancy at 2 weeks is equal to that of a woman in normal physical condition. Conception occurs only towards the end of the second or the beginning of the third seven-day calendar period.
It is necessary to remember the fact that when comparing obstetric and embryonic stages of pregnancy, the first lags behind the second by two weeks.
If the analysis results in a result slightly higher than 5 mU/ml, the gynecologist will send you for a repeat test in a few days. Until the hCG level (from conception) reaches 25 mU/ml, it is considered doubtful and requires confirmation. Remember that you should always compare the results of a study with the standards of the laboratory where they were carried out. Only a doctor can make a comparison in the most accurate way.
If the result is below normal
If the concentration of human chorionic gonadotropin obtained as a result of the analysis does not meet the standard and the deviation is more than 20%, then this is a very alarming sign. First, the doctor prescribes a repeat test. If a low hCG level is confirmed, then this may be a consequence of the following conditions:
- Incorrectly calculated gestational age.
- Regressive pregnancy (frozen pregnancy or fetal death).
- Ectopic pregnancy.
- Delayed embryo development.
- Threat of spontaneous miscarriage.
- Post-term pregnancy (over 40 weeks).
- Chronic placental insufficiency.
To make a more accurate diagnosis, the patient undergoes a mandatory ultrasound examination.
The level of hCG during an ectopic pregnancy is initially slightly below normal, and then the dynamics drop sharply. But tubal or ovarian attachment of the embryo can only be determined with greater accuracy by ultrasound. It is very important to identify in a timely manner ectopic pregnancy, since this condition directly threatens the health and life of a woman. Modern methods of eliminating this condition make it possible to completely preserve reproductive function. Laparoscopic operations are seamless and as gentle as possible. The rehabilitation period with this method of treatment is minimal.
During a frozen pregnancy, the fetus dies, but for some reason it is not excreted from the body. The hCG level initially remains at a certain level, then begins to decrease. In this case, the doctor observes thickening of the uterus, since spontaneous abortion doesn't happen.
Regressive pregnancy can occur both in the early stages and in a later period. The reasons may be varied, but no clear dependence of this condition on specific factors has been identified.
If the indicator is higher than normal
Most often, an elevated hCG level during a generally normal pregnancy is not a dangerous sign. It is often a companion to multiple births or severe toxicosis.
However, if other tests also differ significantly from the norm, then an elevated hCG level may indicate gestosis or diabetes mellitus. This factor is also observed in women taking hormonal drugs.
In addition, an upward difference in the concentration of human chorionic gonadotropin in combination with reduced estriol and ACE (triple extensive test) may indicate the risk of having a child with Down syndrome.
A pregnant woman undergoes two screenings. The first of them is carried out from 11 to 14 weeks after conception. The level of hCG in the mother's blood is measured and if it is elevated, then we are talking about chromosomal mutations. Based on the data obtained, the doctor calculates the likelihood of having a child with Down syndrome or other chromosomal diseases. Typically, children with trisomy have elevated hCG levels. To confirm the blood test, an ultrasound is performed, and then repeated screening at 16-17 weeks. Sometimes it happens that an elevated level of hCG is detected in a completely healthy baby. Then the analysis is carried out amniotic fluid for high precision results.
Before a woman becomes pregnant, many have no idea what hCG is and what role this indicator plays in the process “ interesting situation“and what impact it has on the child’s development.
HCG (human chorionic gonadotropin) is one of the most important indicators indicating not just the presence of pregnancy, but also how successfully it is proceeding. And depending on the stage of pregnancy, this indicator will vary. So, for example, hCG at 5 weeks of pregnancy can be from 2,000 to 83,000! It's pretty individual indicator and may vary for each woman. Therefore, if a woman goes, for example, with a friend to get tested, and they get different data, it’s normal to panic and there’s no need to panic!
Features of the hCG indicator
Human chorionic gonadotropin begins to be produced approximately 6-8 weeks after the egg has been fertilized. HCG stimulates the production of female hormones, which are necessary for the normal development of the fetus and wellness mother.
It is thanks to the increase in hCG levels at week 5 that the expectant mother changes in appearance. This determines the well-known beauty of a pregnant woman, when her eyes glow, there is a blush on her cheeks and the expectant mother becomes like a standard of femininity.
Interesting feature This indicator is also that the longer the pregnancy, the more the hCG level drops. Now doctors can absolutely easily diagnose pregnancy using this indicator, and if a woman has a multiple pregnancy, the hCG indicator increases in accordance with the number of fertilized eggs.
HCG norms at 5 months
Having studied the features of this indicator, almost every woman will be interested in the hCG rate. At 5 weeks, these norms can be very individual. As you know, any standards are quite subjective and the hCG level is no exception. It can vary not only depending on the duration of pregnancy, as ordinary people believe, but also on the laboratory, which “sets its own standards.”
So, if the expectant mother is interested in the question of what hCG should be, then it is worth indicating the following numbers at week 5:
If 3-4 weeks have passed since conception (5-6 obstetric weeks), then the hCG level will be from 1110 to 31500. Due to such a significant difference in the numbers, it is quite difficult to say what hCG should be.
At the stage of 4-5 weeks from conception (6-7 obstetric weeks), hCG can have values from 2560 to 82300.
5-6 weeks from the moment of conception (7-8 obstetric weeks) will be displayed in numbers from 23100 to 151000.
An hCG test can be taken from the very first day of the delay. But if conception occurred less than 14 days ago - reliable results It's almost impossible to expect.
By what principle does hCG increase?
Due to its special influence on the development of the fetus and the well-being of the mother, this indicator is extremely important and you need to know how hCG grows. It is worth noting that in the first weeks, hCG doubles almost every 2-3 days, later it begins to increase once every 3-4 days. After 8-9 obstetric weeks, the hCG level stops growing so actively and begins to decrease, albeit quite slowly.
How does the child develop?
HCG shows how well the baby is developing, and at 5 weeks of pregnancy this indicator is still growing, contributing to its successful development. Thanks to the work of human chorionic gonadotropin, the corpus luteum is “supported” and the necessary female hormones are stimulated, which has a beneficial effect on the baby’s condition. At this stage, he already has certain outlines visible, although he is still very small. An experienced doctor can easily predict the features of its further development. And some predictions are made solely based on the level of hCG at 5 weeks.
Does mom feel hCG levels?
Some mothers do not feel their state of pregnancy at 5 weeks - what can we say about the fact that the hCG level at 5 weeks will not make itself felt! However, a woman may notice some external changes on herself. Thanks to the active work of hormones, the release of which, in fact, is promoted by hCG, the fair sex becomes truly more attractive.
Also, at week 5, a woman may begin to gain weight, and this is not always due to the fact that she has a certain level of hCG or is not what it should be - these are new taste preferences and the appearance of appetite.
At the 5-week stage, the baby's development becomes more active in terms of the formation of more vital organs. And now to the expectant mother It is extremely important to take care of yourself, your health and the future of your child. And doctors who monitor the success of pregnancy will think about hCG levels.